Typical presentation should not be expected in the adult population fewer patients present with diarrhea or a malabsorption syndrome. The clinical presentation among adults has clearly changed over time. CD was previously thought to be a pediatric malabsorption syndrome, but it is now primarily recognized as an adult disease that resembles a multisystem disorder with a range of clinical manifestations that vary according to age of presentation. This paper reviews the current literature in terms of the value of enteroscopy for diagnosis of CD.Ĭeliac disease (CD) is the most common inflammatory disease of the small bowel with a prevalence of 1%-2.1% in different countries. However, both techniques should be reserved for patients with suspected diagnosis of complications. Capsule endoscopy may be a good substitute for enteroscopy. Invasiveness of the method limits its use. Enteroscopy can reveal changes in CD in the intestinal mucosa in 10%-17% of cases that have negative histology at initial workup. To diagnose CD correctly, going deeper in the intestine may be necessary. Unfortunately current endoscopic methods can only diagnose villous atrophy, which can be present in the later grades of disease (i.e., Marsh III). As a result of the widespread use of serology, many patients with equivocal findings grow quickly. However, there is a group of patients with positive serology and inconclusive pathology. It has been shown that duodenal biopsies are good for detection of the disease in most patients. Serological screening may aid in identifying patients with suspected CD, which should be confirmed by intestinal biopsy. Exclusion of dietary gluten is the mainstay of the treatment that necessitates a precise diagnosis of the disease.
Celiac disease (CD) is an autoimmune inflammatory disease of the small intestine as a result of reaction to wheat protein, gluten.
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